Mitochondria and male infertility

"Crucially, the genes that are most affected in males are expressed almost exclusively in the male reproductive organs and associated with male fertility.
"What our results suggest is that the mitochondria have inadvertently evolved to be bad for males, but good for females, as a by-product of their maternal transmission. This might well put the sexes in conflict when it comes to the question of which mitochondrial genes should be passed on to future generations," Dr Dowling said.
"While medical practitioners have a fairly good idea that certain mitochondrial mutations can bring about male infertility, the evolutionary process that we uncover actually suggests that the mitochondria might well harbor very many unidentified mutations, all of which could contribute to the problem of male infertility."

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